Let Go

Deaths

 * Lucas (Flashback)
 * Jake (Flashback)
 * Pat and Jen's families (Confirmed Fate)

Trivia

 * The episode name refers to Harriet telling Jacob that the hardest part about growing up is letting go of what you're used to. It also refers to Brendan & Josue's need to let go of haunting memories: Brendan hallucinating Ethan and getting Coryne & Katie killed, and Josue losing Lucas, Jake, & Neftali. It also refers to Carter & Amber letting go of the stress and pain they've gone through by having sexual relations.